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News for nerds

Level of chromosomal abnormality in lung cancer may predict immunotherapy response

Patients with non-small cell lung cancer (NSCLC) whose cancer cells have low levels of aneuploidy—an abnormal number of chromosomes—tend to respond better to immune checkpoint inhibitor drugs than patients with

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Personalized cancer vaccine is safe, shows potential benefit against cancer

A personalized cancer vaccine developed with the help of a Mount Sinai computational platform raised no safety concerns and showed potential benefit in patients with different cancers, including lung and

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The impact of chemotherapy on immune cells in the tumor microenvironment

Research from Queen Mary University of London has revealed novel insights into the effects of chemotherapy on the tumour microenvironment (TME). The study, published today in Cancer Immunology Research, a

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Immune-stimulating drug before surgery shows promise in early-stage pancreatic cancer

Giving early-stage pancreatic cancer patients a CD40 immune-stimulating drug helped jumpstart a T cell attack to the notoriously stubborn tumor microenvironment before surgery and other treatments, according to a new

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Mutant KRAS and p53 cooperate to drive pancreatic cancer metastasis

Researchers at The University of Texas MD Anderson Cancer Center have discovered that mutant KRAS and p53, the most frequently mutated genes in pancreatic cancer, interact through the CREB1 protein

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Reese’s wants to give you a peanut butter glow up

Reese’s is launching its own makeup line — and no, it’s not edible. The candy brand is teaming up with makeup company HipDot for a limited-edition collection that includes a

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Isn’t it irenic? It’s time to bring back beautiful words we have lost

I was trying to make a small impression on my pile of unread editions of the London Review of Books at the weekend. I’ve been stuck at base camp for

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